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Image Search Results
Journal: Experimental and Therapeutic Medicine
Article Title: Effectiveness of imatinib mesylate over etoposide in the treatment of sensitive and resistant chronic myeloid leukaemia cells in vitro
doi: 10.3892/etm.2017.4443
Figure Lengend Snippet: Apoptotic rate of K562 cell lines following imatinib mesylate or etoposide treatment, as detemined by a terminal deoxynucleotidyl transferase dUTP nick end labeling assay. The fluorescent images of (A) apoptotic K562 cells and (B) apoptotic K562/ADM cells were obtained following treatment with 0.5 µM imatinib mesylate or 50 µM etoposide 48 h. Co-fluorescent cell nuclei (blue DAPI stain) and damaged DNA (green fluorescein isothiocyanate stain) indicated apoptotic cells. Representative images of ≥2 independent experiments are presented. Magnification, ×100; insert magnification, ×400. (C) Apoptotic cells were counted and their percentage determined. Values represent the mean ± standard deviation. *P<0.05; not significant (ns) P>0.05. K562, parental sensitive chronic myeloid leukaemia cell line; K562/ADM, adriamycin-resistant chronic myeloid leukaemia cell line; FITC, fluorescein isothiocyanate.
Article Snippet: Following this, a
Techniques: TUNEL Assay, Staining, Standard Deviation